Pain in knee osteoarthritis patients associates with distinct pattern of synovitis

De:

1. B.J.E. deLange-Brokaar¹, 
2. A Ioan-Facsinay¹, 
3. E Yusuf¹, 
4. A.W. Visser¹, 
5. H.M. Kroon⁵,
6. G.J.V.M. vanOsch², 
7. A-M. Zuurmond³, 
8. V Stojanovic-Susulic⁴, 
9. J.L. Bloem⁵, 
10. R.G.H.H. Nelissen⁶, 
11. T.W. Huizinga¹ and
12. M Kloppenburg^1,7,*

DOI: 10.1002/art.38965

Copyright © 2014 American College of Rheumatology

Pain in knee osteoarthritis patients associates with distinct pattern of synovitis

#Pain in #knee #osteoarthritis patients associates w/ distinct pattern of synovitis

http://onlinelibrary.wiley.com/doi/10.1002/art.38965/abstract

Preview Article

http://onlinelibrary.wiley.com/doi/10.1002/art.38965/pdf

Keywords:

• knee osteoarthritis;
• synovitis;
• pain;
• MRI;
• radiographic severity

ABSTRACT

Objective: To determine patterns of synovitis on contrast-enhanced magnetic resonance images and its relation to pain and severity of radiographic OA. Methods: 86 patients (mean age 62 years, 66% woman, median BMI 29 kg/mm² and Kellgren-Lawrence score 3 ) with symptomatic knee OA were included. T1-weighted Gd-chelate-enhanced MRI with fat-suppression (3T) were used to semi-quantitatively score synovitis at 11 sites (range 0-22). Self-reported pain was assessed by standardized questionnaires...

Conclusion: Different patterns of synovitis in knee OA were observed. The pattern including several patellar sites was associated with pain, whereas other patterns were not, suggesting a localized response in pain perception in knee OA patients. This article is protected by copyright. All rights reserved.