Artroscopia y reconstrucción articular

miércoles, 26 de noviembre de 2014

Pain in knee osteoarthritis patients associates with distinct pattern of synovitis

  1. B.J.E. deLange-Brokaar1
  2. A Ioan-Facsinay1
  3. E Yusuf1
  4. A.W. Visser1
  5. H.M. Kroon5,
  6. G.J.V.M. vanOsch2
  7. A-M. Zuurmond3
  8. V Stojanovic-Susulic4
  9. J.L. Bloem5
  10. R.G.H.H. Nelissen6
  11. T.W. Huizinga1 and
  12. M Kloppenburg1,7,*
DOI: 10.1002/art.38965

Preview Article


  • knee osteoarthritis;
  • synovitis;
  • pain;
  • MRI;
  • radiographic severity


Objective: To determine patterns of synovitis on contrast-enhanced magnetic resonance images and its relation to pain and severity of radiographic OA. Methods: 86 patients (mean age 62 years, 66% woman, median BMI 29 kg/mm2 and Kellgren-Lawrence score 3 ) with symptomatic knee OA were included. T1-weighted Gd-chelate-enhanced MRI with fat-suppression (3T) were used to semi-quantitatively score synovitis at 11 sites (range 0-22). Self-reported pain was assessed by standardized questionnaires...
Conclusion: Different patterns of synovitis in knee OA were observed. The pattern including several patellar sites was associated with pain, whereas other patterns were not, suggesting a localized response in pain perception in knee OA patients. This article is protected by copyright. All rights reserved.

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